Optimization of Xylazine-Ketamine Anesthetic Dose in Mice with Chronic Liver Injury
نویسندگان
چکیده
منابع مشابه
Anesthetic effects and body weight changes associated with ketamine-xylazine-lidocaine administered to CD-1 mice
Anesthesia for mice is commonly performed through the injection of parenteral agents via the intraperitoneal (IP) route. Variability in anesthetic sensitivities has been noted in mice resulting in inconsistencies in anesthetic depth and/or mortality. Anesthetic protocols that improve consistency and safety are needed. The objectives of this study were to assess the effects of intraperitoneal (I...
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PURPOSE We have observed that the commonly used ketamine/xylazine anesthesia mix can induce a focally severe and permanent corneal opacity. The purpose of this study was to establish the clinical and histological features of this deleterious side effect, its sensitivity with respect to age and anesthesia protocol, and approaches for avoiding it. METHODS Young C57BL/6J, C57BLKS/J, and SJL/J mi...
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Objectives: To evaluate if epidural administration of xylazine could decrease the effective dose of intravenous ketamine for maintenance of general anesthesia in laparoscopic procedures and assessment of related complications during anesthesia. Design: Experimental Study. Animals: 20 Female dogs with 21.0 ± 3.0 kg weight and 18.0 ± 1.2 months age. Material and methods: Animals randomly divid...
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The influence of increasing the dosage of ketamine on anaesthesia induced by a combination of ketamine, xylazine and midazolam in pigs was determined by assessing the onset of action (OAN), duration of analgesia (DAN), anaesthesia time (ANT), and recovery time (RCT) in 10 growing pigs (Mean weight: 18.2 +/- 1.65 kg) receiving either 10 mg/kg intramuscular (i.m.) injection of 10% ketamine, 2 mg/...
متن کاملComparison of ketamine-diazepam with ketamine-xylazine anesthetic combinations in sheep spontaneously breathing and undergoing maxillofacial surgery.
The objective of this study was to choose a suitable anesthetic combination for use in experimental surgical models by comparing the anesthetic and cardio-respiratory changes. Fourteen healthy male sheep were randomly assigned to two different drug regimens. In Group 1 the sheep were anesthetized with ketamine + xylazine (22 mg/kg im. + 0.2 mg/kg i.m., respectively). Anesthetic combination of k...
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ژورنال
عنوان ژورنال: Egyptian Academic Journal of Biological Sciences, B. Zoology
سال: 2019
ISSN: 2090-0821
DOI: 10.21608/eajbsz.2019.28307